L10V (p.Leu10Val) variant of NTRK1 (P04629)
L10V (p.Leu10Val) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L10V (p.Leu10Val) variant details
- p.Leu10Val
- Ensembl rs1655615857
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.09
- MetaLR 0.13
- MetaSVM -0.96
- CADD 12.40
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available