L10F (p.Leu10Phe) variant of NTRK1 (P04629)
L10F (p.Leu10Phe) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L10F (p.Leu10Phe) variant details
- p.Leu10Phe
- cosmic curated COSV62325
- Ensembl rs1655615857
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.09
- MetaLR 0.15
- MetaSVM -0.91
- CADD 14.00
- PolyPhen-2 0.02
- SIFT 0.04
- Most common in the 1KG:IBS population (allele frequency 0.017)
- Structural context available