G18W (p.Gly18Trp) variant of NTRK1 (P04629)
G18W (p.Gly18Trp) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
G18W (p.Gly18Trp) variant details
- p.Gly18Trp
- gnomAD 1-156860986-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.417
- REVEL 0.30
- MetaLR 0.40
- MetaSVM -0.61
- CADD 22.80
- PolyPhen-2 0.42
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available