G11S (p.Gly11Ser) variant of NTRK1 (P04629)
G11S (p.Gly11Ser) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data, published literature, and structural context.
G11S (p.Gly11Ser) variant details
- p.Gly11Ser
- gnomAD 1-156860965-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.171
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.04
- CADD 13.20
- PolyPhen-2 0.02
- SIFT 0.28
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available
- Literature evidence available