A24D (p.Ala24Asp) variant of NTRK1 (P04629)
A24D (p.Ala24Asp) in NTRK1 (P04629) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
A24D (p.Ala24Asp) variant details
- p.Ala24Asp
- gnomAD 1-156861005-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.32
- MetaLR 0.15
- MetaSVM -0.95
- CADD 21.20
- PolyPhen-2 0.05
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.6e-05)
- Structural context available
- Literature evidence available