Y68H (p.Tyr68His) variant of NRXN2 (Neurexin-2)
Y68H (p.Tyr68His) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
Y68H (p.Tyr68His) variant details
- p.Tyr68His
- ExAC rs764121263
- gnomAD rs764121263
- Missense
- Variant Prioritization Score for Impact Estimate 0.704
- REVEL 0.80
- MetaLR 0.65
- MetaSVM 0.33
- CADD 28.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available