W7C (p.Trp7Cys) variant of NRXN2 (Neurexin-2)
W7C (p.Trp7Cys) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
W7C (p.Trp7Cys) variant details
- p.Trp7Cys
- gnomAD rs1195602931
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.08
- MetaLR 0.11
- MetaSVM -0.93
- CADD 22.10
- PolyPhen-2 0.02
- SIFT 0.08
- Population evidence available
- Structural context available