V137G (p.Val137Gly) variant of NRXN2 (Neurexin-2)
V137G (p.Val137Gly) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
V137G (p.Val137Gly) variant details
- p.Val137Gly
- Ensembl rs2135675478
- Missense
- Variant Prioritization Score for Impact Estimate 0.61
- REVEL 0.70
- MetaLR 0.65
- MetaSVM 0.36
- CADD 24.00
- PolyPhen-2 0.07
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.8e-05)
- Structural context available