T92M (p.Thr92Met) variant of NRXN2 (Neurexin-2)
T92M (p.Thr92Met) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
T92M (p.Thr92Met) variant details
- p.Thr92Met
- TOPMed rs915873153
- gnomAD rs915873153
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.35
- MetaLR 0.41
- MetaSVM -0.25
- CADD 22.70
- PolyPhen-2 0.29
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available