T100M (p.Thr100Met) variant of NRXN2 (Neurexin-2)
T100M (p.Thr100Met) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
T100M (p.Thr100Met) variant details
- p.Thr100Met
- gnomAD rs1267435128
- Missense
- Variant Prioritization Score for Impact Estimate 0.597
- REVEL 0.54
- MetaLR 0.55
- MetaSVM 0.03
- CADD 26.00
- PolyPhen-2 0.92
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 7.6e-06)
- Structural context available