R141W (p.Arg141Trp) variant of NRXN2 (Neurexin-2)
R141W (p.Arg141Trp) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
R141W (p.Arg141Trp) variant details
- p.Arg141Trp
- cosmic curated COSV55454
- gnomAD rs1207761672
- Missense
- Variant Prioritization Score for Impact Estimate 0.756
- REVEL 0.81
- MetaLR 0.61
- MetaSVM 0.34
- CADD 26.60
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available