R133G (p.Arg133Gly) variant of NRXN2 (Neurexin-2)
R133G (p.Arg133Gly) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R133G (p.Arg133Gly) variant details
- p.Arg133Gly
- gnomAD rs2057125564
- Missense
- Variant Prioritization Score for Impact Estimate 0.349
- REVEL 0.20
- MetaLR 0.21
- MetaSVM -0.79
- CADD 22.70
- PolyPhen-2 0.02
- SIFT 0.10
- Population evidence available
- Structural context available