P9S (p.Pro9Ser) variant of NRXN2 (Neurexin-2)
P9S (p.Pro9Ser) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
P9S (p.Pro9Ser) variant details
- p.Pro9Ser
- gnomAD rs1468924026
- Missense
- Variant Prioritization Score for Impact Estimate 0.185
- REVEL 0.06
- MetaLR 0.10
- MetaSVM -1.04
- CADD 17.40
- PolyPhen-2 0.00
- SIFT 0.23
- Most common in the South Asian population (allele frequency 4.8e-05)
- Structural context available