P98S (p.Pro98Ser) variant of NRXN2 (Neurexin-2)
P98S (p.Pro98Ser) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
P98S (p.Pro98Ser) variant details
- p.Pro98Ser
- TOPMed rs1418733682
- gnomAD rs1418733682
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- REVEL 0.42
- MetaLR 0.48
- MetaSVM -0.03
- CADD 22.00
- PolyPhen-2 0.22
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 3.2e-05)
- Structural context available