P12T (p.Pro12Thr) variant of NRXN2 (Neurexin-2)
P12T (p.Pro12Thr) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P12T (p.Pro12Thr) variant details
- p.Pro12Thr
- gnomAD rs1273507123
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.04
- MetaLR 0.07
- MetaSVM -1.02
- CADD 5.44
- PolyPhen-2 0.00
- SIFT 0.29
- Population evidence available
- Structural context available