L93V (p.Leu93Val) variant of NRXN2 (Neurexin-2)
L93V (p.Leu93Val) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L93V (p.Leu93Val) variant details
- p.Leu93Val
- TOPMed rs1408459116
- gnomAD rs1408459116
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.09
- MetaLR 0.30
- MetaSVM -0.73
- CADD 17.90
- PolyPhen-2 0.02
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available