L80P (p.Leu80Pro) variant of NRXN2 (Neurexin-2)
L80P (p.Leu80Pro) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
L80P (p.Leu80Pro) variant details
- p.Leu80Pro
- gnomAD rs1465281239
- Missense
- Variant Prioritization Score for Impact Estimate 0.71
- REVEL 0.76
- MetaLR 0.77
- MetaSVM 0.56
- CADD 27.60
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available