L78P (p.Leu78Pro) variant of NRXN2 (Neurexin-2)
L78P (p.Leu78Pro) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
L78P (p.Leu78Pro) variant details
- p.Leu78Pro
- gnomAD rs1188023252
- Missense
- Variant Prioritization Score for Impact Estimate 0.679
- REVEL 0.75
- MetaLR 0.64
- MetaSVM 0.19
- CADD 28.20
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available