L65V (p.Leu65Val) variant of NRXN2 (Neurexin-2)
L65V (p.Leu65Val) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
L65V (p.Leu65Val) variant details
- p.Leu65Val
- ExAC rs767883855
- gnomAD rs767883855
- Missense
- Variant Prioritization Score for Impact Estimate 0.554
- REVEL 0.62
- MetaLR 0.55
- MetaSVM -0.02
- CADD 24.30
- PolyPhen-2 0.96
- SIFT 0.11
- Population evidence available
- Structural context available