L16F (p.Leu16Phe) variant of NRXN2 (Neurexin-2)
L16F (p.Leu16Phe) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L16F (p.Leu16Phe) variant details
- p.Leu16Phe
- TOPMed rs1023018857
- gnomAD rs1023018857
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.06
- MetaLR 0.16
- MetaSVM -0.93
- CADD 8.23
- PolyPhen-2 0.00
- SIFT 0.15
- Population evidence available
- Structural context available