L14P (p.Leu14Pro) variant of NRXN2 (Neurexin-2)
L14P (p.Leu14Pro) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
L14P (p.Leu14Pro) variant details
- p.Leu14Pro
- gnomAD rs1328834551
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.15
- MetaLR 0.09
- MetaSVM -1.05
- CADD 8.85
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available