G85D (p.Gly85Asp) variant of NRXN2 (Neurexin-2)
G85D (p.Gly85Asp) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
G85D (p.Gly85Asp) variant details
- p.Gly85Asp
- gnomAD rs866122162
- Missense
- Variant Prioritization Score for Impact Estimate 0.769
- REVEL 0.77
- MetaLR 0.80
- MetaSVM 0.80
- CADD 25.50
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.8e-05)
- Structural context available