G72S (p.Gly72Ser) variant of NRXN2 (Neurexin-2)
G72S (p.Gly72Ser) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G72S (p.Gly72Ser) variant details
- p.Gly72Ser
- TOPMed rs1041650760
- gnomAD rs1041650760
- Missense
- Variant Prioritization Score for Impact Estimate 0.511
- REVEL 0.40
- MetaLR 0.49
- MetaSVM -0.13
- CADD 26.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available