G51S (p.Gly51Ser) variant of NRXN2 (Neurexin-2)
G51S (p.Gly51Ser) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
G51S (p.Gly51Ser) variant details
- p.Gly51Ser
- gnomAD rs1316250997
- Missense
- Variant Prioritization Score for Impact Estimate 0.423
- REVEL 0.28
- MetaLR 0.25
- MetaSVM -0.80
- CADD 21.60
- PolyPhen-2 0.04
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.7e-07)
- Structural context available