G51D (p.Gly51Asp) variant of NRXN2 (Neurexin-2)
G51D (p.Gly51Asp) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
G51D (p.Gly51Asp) variant details
- p.Gly51Asp
- ExAC rs745555224
- TOPMed rs745555224
- gnomAD rs745555224
- Missense
- Variant Prioritization Score for Impact Estimate 0.572
- REVEL 0.52
- MetaLR 0.54
- MetaSVM 0.08
- CADD 23.30
- PolyPhen-2 0.04
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 0.0002)
- Structural context available