G46R (p.Gly46Arg) variant of NRXN2 (Neurexin-2)
G46R (p.Gly46Arg) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G46R (p.Gly46Arg) variant details
- p.Gly46Arg
- ExAC rs768737747
- gnomAD rs768737747
- Missense
- Variant Prioritization Score for Impact Estimate 0.516
- CADD 17.10
- SIFT 0.03
- Most common in the Amish population (allele frequency 0.0022)
- Structural context available