G33C (p.Gly33Cys) variant of NRXN2 (Neurexin-2)
G33C (p.Gly33Cys) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
G33C (p.Gly33Cys) variant details
- p.Gly33Cys
- gnomAD rs1169656292
- Missense
- Variant Prioritization Score for Impact Estimate 0.753
- REVEL 0.79
- MetaLR 0.69
- MetaSVM 0.49
- CADD 26.50
- PolyPhen-2 0.86
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 2.1e-05)
- Structural context available