G32D (p.Gly32Asp) variant of NRXN2 (Neurexin-2)
G32D (p.Gly32Asp) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
G32D (p.Gly32Asp) variant details
- p.Gly32Asp
- gnomAD rs1354724066
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.11
- AlphaMissense 0.13
- MetaLR 0.06
- MetaSVM -1.05
- CADD 19.00
- PolyPhen-2 0.33
- Most common in the HGDP:RUSSIAN population (allele frequency 0.02)
- Structural context available