G154D (p.Gly154Asp) variant of NRXN2 (Neurexin-2)
G154D (p.Gly154Asp) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
G154D (p.Gly154Asp) variant details
- p.Gly154Asp
- ExAC rs199786530
- gnomAD rs199786530
- Missense
- Variant Prioritization Score for Impact Estimate 0.857
- REVEL 0.93
- MetaLR 0.85
- MetaSVM 0.90
- CADD 26.30
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available