G154C (p.Gly154Cys) variant of NRXN2 (Neurexin-2)
G154C (p.Gly154Cys) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.85 / 1. The record also includes population frequency data and structural context.
G154C (p.Gly154Cys) variant details
- p.Gly154Cys
- gnomAD rs1347724629
- Missense
- Variant Prioritization Score for Impact Estimate 0.85
- REVEL 0.90
- MetaLR 0.85
- MetaSVM 0.90
- CADD 28.40
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available