F91L (p.Phe91Leu) variant of NRXN2 (Neurexin-2)
F91L (p.Phe91Leu) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
F91L (p.Phe91Leu) variant details
- p.Phe91Leu
- ExAC rs757559993
- gnomAD rs757559993
- Missense
- Variant Prioritization Score for Impact Estimate 0.587
- REVEL 0.68
- MetaLR 0.51
- MetaSVM -0.04
- CADD 24.60
- PolyPhen-2 0.58
- SIFT 0.00
- Population evidence available
- Structural context available