F77S (p.Phe77Ser) variant of NRXN2 (Neurexin-2)
F77S (p.Phe77Ser) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
F77S (p.Phe77Ser) variant details
- p.Phe77Ser
- ExAC rs776095862
- Missense
- Variant Prioritization Score for Impact Estimate 0.69
- REVEL 0.78
- MetaLR 0.62
- MetaSVM 0.15
- CADD 29.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.7e-05)
- Structural context available