F55L (p.Phe55Leu) variant of NRXN2 (Neurexin-2)
F55L (p.Phe55Leu) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
F55L (p.Phe55Leu) variant details
- p.Phe55Leu
- ExAC rs748532027
- gnomAD rs748532027
- Missense
- Variant Prioritization Score for Impact Estimate 0.565
- REVEL 0.62
- MetaLR 0.43
- MetaSVM -0.39
- CADD 24.50
- PolyPhen-2 0.72
- SIFT 0.06
- Population evidence available
- Structural context available