D74Y (p.Asp74Tyr) variant of NRXN2 (Neurexin-2)
D74Y (p.Asp74Tyr) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
D74Y (p.Asp74Tyr) variant details
- p.Asp74Tyr
- ExAC rs775042347
- TOPMed rs775042347
- gnomAD rs775042347
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.16
- MetaLR 0.16
- MetaSVM -0.86
- CADD 16.10
- PolyPhen-2 0.03
- SIFT 0.06
- Population evidence available
- Structural context available