D27E (p.Asp27Glu) variant of NRXN2 (Neurexin-2)
D27E (p.Asp27Glu) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
D27E (p.Asp27Glu) variant details
- p.Asp27Glu
- TOPMed rs959867285
- gnomAD rs959867285
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.11
- MetaLR 0.18
- MetaSVM -0.99
- CADD 4.74
- PolyPhen-2 0.00
- SIFT 0.97
- Population evidence available
- Structural context available