D158N (p.Asp158Asn) variant of NRXN2 (Neurexin-2)
D158N (p.Asp158Asn) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
D158N (p.Asp158Asn) variant details
- p.Asp158Asn
- gnomAD rs1238368226
- Missense
- Variant Prioritization Score for Impact Estimate 0.543
- REVEL 0.47
- MetaLR 0.51
- MetaSVM -0.17
- CADD 22.90
- PolyPhen-2 0.36
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 3.8e-06)
- Structural context available