D149N (p.Asp149Asn) variant of NRXN2 (Neurexin-2)
D149N (p.Asp149Asn) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
D149N (p.Asp149Asn) variant details
- p.Asp149Asn
- ExAC rs780377622
- TOPMed rs780377622
- gnomAD rs780377622
- Missense
- Variant Prioritization Score for Impact Estimate 0.6
- REVEL 0.55
- MetaLR 0.53
- MetaSVM 0.06
- CADD 25.60
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.9e-05)
- Structural context available