D109E (p.Asp109Glu) variant of NRXN2 (Neurexin-2)
D109E (p.Asp109Glu) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
D109E (p.Asp109Glu) variant details
- p.Asp109Glu
- 1000Genomes rs765238870
- ExAC rs765238870
- TOPMed rs765238870
- gnomAD rs765238870
- Missense
- Variant Prioritization Score for Impact Estimate 0.615
- REVEL 0.66
- MetaLR 0.76
- MetaSVM 0.39
- CADD 25.60
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available