C75G (p.Cys75Gly) variant of NRXN2 (Neurexin-2)
C75G (p.Cys75Gly) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
C75G (p.Cys75Gly) variant details
- p.Cys75Gly
- ExAC rs769227620
- TOPMed rs769227620
- gnomAD rs769227620
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.63
- MetaLR 0.47
- MetaSVM -0.22
- CADD 23.10
- PolyPhen-2 0.42
- SIFT 0.00
- Population evidence available
- Structural context available