A26V (p.Ala26Val) variant of NRXN2 (Neurexin-2)
A26V (p.Ala26Val) in NRXN2 (Neurexin-2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A26V (p.Ala26Val) variant details
- p.Ala26Val
- TOPMed rs1265312936
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.08
- AlphaMissense 0.11
- MetaLR 0.07
- MetaSVM -1.09
- CADD 14.10
- PolyPhen-2 0.01
- Most common in the Non-Finnish European population (allele frequency 2.1e-06)
- Structural context available