W24S (p.Trp24Ser) variant of NRXN1 (Neurexin-1)
W24S (p.Trp24Ser) in NRXN1 (Neurexin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
W24S (p.Trp24Ser) variant details
- p.Trp24Ser
- gnomAD rs1670920288
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.33
- CADD 22.80
- PolyPhen-2 0.01
- SIFT 0.20
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available