W24C (p.Trp24Cys) variant of NRXN1 (Neurexin-1)
W24C (p.Trp24Cys) in NRXN1 (Neurexin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
W24C (p.Trp24Cys) variant details
- p.Trp24Cys
- gnomAD rs1477139182
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.39
- CADD 22.80
- PolyPhen-2 0.09
- SIFT 0.04
- Population evidence available
- Structural context available