R61L (p.Arg61Leu) variant of NRXN1 (Neurexin-1)
R61L (p.Arg61Leu) in NRXN1 (Neurexin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
R61L (p.Arg61Leu) variant details
- p.Arg61Leu
- ExAC rs202205785
- gnomAD rs202205785
- Missense
- Variant Prioritization Score for Impact Estimate 0.526
- REVEL 0.45
- CADD 23.00
- PolyPhen-2 0.17
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available