R42G (p.Arg42Gly) variant of NRXN1 (Neurexin-1)
R42G (p.Arg42Gly) in NRXN1 (Neurexin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.68 / 1. The record also includes population frequency data and structural context.
R42G (p.Arg42Gly) variant details
- p.Arg42Gly
- TOPMed rs1365577683
- gnomAD rs1365577683
- Missense
- Variant Prioritization Score for Impact Estimate 0.681
- REVEL 0.68
- CADD 26.90
- PolyPhen-2 0.84
- SIFT 0.01
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.7e-05)
- Structural context available