G35S (p.Gly35Ser) variant of NRXN1 (Neurexin-1)
G35S (p.Gly35Ser) in NRXN1 (Neurexin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
G35S (p.Gly35Ser) variant details
- p.Gly35Ser
- TOPMed rs1460174762
- gnomAD rs1460174762
- Missense
- Variant Prioritization Score for Impact Estimate 0.771
- REVEL 0.76
- CADD 26.20
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available