C23Y (p.Cys23Tyr) variant of NRXN1 (Neurexin-1)
C23Y (p.Cys23Tyr) in NRXN1 (Neurexin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
C23Y (p.Cys23Tyr) variant details
- p.Cys23Tyr
- Ensembl rs1670921246
- Missense
- Variant Prioritization Score for Impact Estimate 0.669
- REVEL 0.61
- CADD 23.70
- PolyPhen-2 0.36
- SIFT 0.25
- Most common in the East Asian population (allele frequency 2.7e-05)
- Structural context available