A25S (p.Ala25Ser) variant of NRXN1 (Neurexin-1)
A25S (p.Ala25Ser) in NRXN1 (Neurexin-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
A25S (p.Ala25Ser) variant details
- p.Ala25Ser
- cosmic curated COSV68012
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- REVEL 0.30
- CADD 21.20
- PolyPhen-2 0.07
- SIFT 0.15
- Most common in the REMAINING population (allele frequency 1.8e-05)
- Structural context available