S71R (p.Ser71Arg) variant of NR3C1 (Glucocorticoid receptor)
S71R (p.Ser71Arg) in NR3C1 (Glucocorticoid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, experimental measurements, and structural context.
S71R (p.Ser71Arg) variant details
- p.Ser71Arg
- gnomAD rs1477109172
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.09
- CADD 23.10
- PolyPhen-2 0.80
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- NR3C1 Zinc finger, nuclear hormone receptor-type domain domainome 1.0: score -0.131