S111G (p.Ser111Gly) variant of NR3C1 (Glucocorticoid receptor)
S111G (p.Ser111Gly) in NR3C1 (Glucocorticoid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data.
S111G (p.Ser111Gly) variant details
- p.Ser111Gly
- TOPMed rs941700497
- gnomAD rs941700497
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.03
- CADD 19.40
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the African/African-American population (allele frequency 2.4e-05)