P105R (p.Pro105Arg) variant of NR3C1 (Glucocorticoid receptor)
P105R (p.Pro105Arg) in NR3C1 (Glucocorticoid receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data.
P105R (p.Pro105Arg) variant details
- p.Pro105Arg
- TOPMed rs1353083246
- gnomAD rs1353083246
- Missense
- Variant Prioritization Score for Impact Estimate 0.459
- REVEL 0.21
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the South Asian population (allele frequency 1.2e-05)